The nucleolus (, plural: nucleoli ) is the largest structure in the nucleus of eukaryotic cells. It is best known as the site of ribosome biogenesis. Nucleoli also participate in the formation of signal recognition particles and play a role in the cell’s response to stress. Nucleoli are made of proteins, DNA and RNA and form around specific chromosomal regions called nucleolar organizing regions. Malfunction of nucleoli can be the cause of several human conditions called “nucleolopathies” and the nucleolus is being investigated as a target for cancer chemotherapy.
The core, central part of something, around which other elements are assembled.
An initial part or version that will receive additions.
“This collection will form the nucleus of a new library.”
The massive, positively charged central part of an atom, made up of protons and neutrons.
A large membrane-enclosed organelle found in eukaryotic cells which contains genetic material.
A synapsing occurs.
The central part of a syllable, most commonly a vowel.
A conspicuous, rounded body within the nucleus of a cell.