Main Difference
The main difference between Ketone and Phenone is that the Ketone is a class of organic compounds having structure RCOR´ and Phenone is a Wiktionary redirect.
Ketone
In chemistry, a ketone (alkanone) is an organic compound with the structure RC(=O)R’, where R and R’ can be a variety of carbon-containing substituents. Ketones and aldehydes are simple compounds that contain a carbonyl group (a carbon-oxygen double bond). They are considered “simple” because they do not have reactive groups like −OH or −Cl attached directly to the carbon atom in the carbonyl group, as in carboxylic acids containing −COOH. Many ketones are known and many are of great importance in industry and in biology. Examples include many sugars (ketoses) and the industrial solvent acetone, which is the smallest ketone.
Ketone (noun)
A homologous series of organic molecules whose functional group is an oxygen atom joined to a carbon atom—by a double bond—in a carbon-hydrogen based molecule.
Phenone (noun)
Any aromatic ketone containing a phenyl group directly attached to the carbonyl group