Cytoplasm vs. Nucleoplasm

By Jaxson

Main Difference

The main difference between Cytoplasm and Nucleoplasm is that the Cytoplasm is a All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures and Nucleoplasm is a that part of the nuclear content other than the chromosomes or the nucleolus

  • Cytoplasm

    In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus. It comprises cytosol (the gel-like substance enclosed within the cell membrane) and the organelles – the cell’s internal sub-structures. All of the contents of the cells of prokaryotic organisms (such as bacteria, which lack a cell nucleus) are contained within the cytoplasm. Within the cells of eukaryotic organisms the contents of the cell nucleus are separated from the cytoplasm, and are then called the nucleoplasm. The cytoplasm is about 80% water and usually colorless.

    The submicroscopic ground cell substance or cytoplasmatic matrix which remains after exclusion the cell organelles and particles is groundplasm. It is the hyaloplasm of light microscopy, and high complex, polyphasic system in which all of resolvable cytoplasmic elements of are suspended, including the larger organelles such as the ribosomes, mitochondria, the plant plastids, lipid droplets, and vacuoles.

    It is within the cytoplasm that most cellular activities occur, such as many metabolic pathways including glycolysis, and processes such as cell division. The concentrated inner area is called the endoplasm and the outer layer is called the cell cortex or the ectoplasm.

    Movement of calcium ions in and out of the cytoplasm is a signaling activity for metabolic processes.

    In plants, movement of the cytoplasm around vacuoles is known as cytoplasmic streaming.

  • Nucleoplasm

    Similar to the cytoplasm of a cell, the nucleus contains nucleoplasm, also known as karyoplasm, or karyolymph or nucleus sap. The nucleoplasm is a type of protoplasm, and is enveloped by the nuclear envelope (also known as the nuclear membrane). The nucleoplasm includes the chromosomes and nucleolus. Many substances such as nucleotides (necessary for purposes such as DNA replication) and enzymes (which direct activities that take place in the nucleus) are dissolved in the nucleoplasm. The soluble, liquid portion of the nucleoplasm is called the nucleosol or nuclear hyaloplasm.

  • Cytoplasm (noun)

    The contents of a cell except for the nucleus. It includes cytosol, organelles, vesicles, and the cytoskeleton.

  • Nucleoplasm (noun)

    The protoplasm of a cell nucleus


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