Cocaine
Cocaine, also known as coke, is a strong stimulant mostly used as a recreational drug. It is commonly snorted, inhaled as smoke, or dissolved and injected into a vein. Mental effects may include loss of contact with reality, an intense feeling of happiness, or agitation. Physical symptoms may include a fast heart rate, sweating, and large pupils. High doses can result in very high blood pressure or body temperature. Effects begin within seconds to minutes of use and last between five and ninety minutes. Cocaine has a small number of accepted medical uses such as numbing and decreasing bleeding during nasal surgery.Cocaine is addictive due to its effect on the reward pathway in the brain. After a short period of use, there is a high risk that dependence will occur. Its use also increases the risk of stroke, myocardial infarction, lung problems in those who smoke it, blood infections, and sudden cardiac death. Cocaine sold on the street is commonly mixed with local anesthetics, cornstarch, quinine, or sugar, which can result in additional toxicity. Following repeated doses a person may have decreased ability to feel pleasure and be very physically tired.Cocaine acts by inhibiting the reuptake of serotonin, norepinephrine, and dopamine. This results in greater concentrations of these three neurotransmitters in the brain. It can easily cross the blood–brain barrier and may lead to the breakdown of the barrier. Cocaine is a naturally occurring substance found in the coca plant which is mostly grown in South America. In 2013, 419 kilograms were produced legally. It is estimated that the illegal market for cocaine is 100 to US$500 billion each year. With further processing crack cocaine can be produced from cocaine.Cocaine is the second most frequently used illegal drug globally, after cannabis. Between 14 and 21 million people use the drug each year. Use is highest in North America followed by Europe and South America. Between one and three percent of people in the developed world have used cocaine at some point in their life. In 2013, cocaine use directly resulted in 4,300 deaths, up from 2,400 in 1990. The leaves of the coca plant have been used by Peruvians since ancient times. Cocaine was first isolated from the leaves in 1860. Since 1961, the international Single Convention on Narcotic Drugs has required countries to make recreational use of cocaine a crime.
Cocaine (noun)
A stimulant narcotic, derived from cultivated plants of the genus noshow=1, in the form of a white powder that users generally self-administer by insufflation through the nose.
Cocaine (noun)
Any derivative of cocaine.
Crack (verb)
To form cracks.
“It’s been so dry, the ground is starting to crack.”
Crack (verb)
To break apart under pressure.
“When I tried to stand on the chair, it cracked.”
Crack (verb)
To become debilitated by psychological pressure.
“Anyone would crack after being hounded like that.”
Crack (verb)
To break down or yield, especially under interrogation or torture.
“When we showed him the pictures of the murder scene, he cracked.”
Crack (verb)
To make a cracking sound.
“The bat cracked with authority and the ball went for six.”
Crack (verb)
To change rapidly in register.
“His voice cracked with emotion.”
Crack (verb)
To alternate between high and low register in the process of eventually lowering.
“His voice finally cracked when he was fourteen.”
Crack (verb)
To make a sharply humorous comment.
“”I would too, with a face like that,” she cracked.”
Crack (verb)
To make a crack or cracks in.
“The ball cracked the window.”
Crack (verb)
To break open or crush to small pieces by impact or stress.
“You’ll need a hammer to crack a black walnut.”
Crack (verb)
To strike forcefully.
“She cracked him over the head with her handbag.”
Crack (verb)
To open slightly.
“Could you please crack the window?”
Crack (verb)
To cause to yield under interrogation or other pressure. (Figurative)
“They managed to crack him on the third day.”
Crack (verb)
To solve a difficult problem. Figurative, from cracking a nut.
“I’ve finally cracked it, and of course the answer is obvious in hindsight.”
Crack (verb)
To overcome a security system or a component.
“It took a minute to crack the lock, three minutes to crack the security system, and about twenty minutes to crack the safe.”
“They finally cracked the code.”
Crack (verb)
To cause to make a sharp sound.
“to crack a whip”
Crack (verb)
To tell (a joke).
“The performance was fine until he cracked that dead baby joke.”
Crack (verb)
To break down (a complex molecule), especially with the application of heat: to pyrolyse.
“Acetone is cracked to ketene and methane at 700°C.”
Crack (verb)
To circumvent software restrictions such as regional coding or time limits.
“That software licence will expire tomorrow unless we can crack it.”
Crack (verb)
To open a canned beverage, or any packaged drink or food.
“I’d love to crack open a beer.”
“Let’s crack a tube and watch the game.””
Crack (verb)
To brag, boast.
Crack (verb)
To be ruined or impaired; to fail.
Crack (noun)
A thin and usually jagged space opened in a previously solid material.
“A large crack had formed in the roadway.”
Crack (noun)
A narrow opening.
“We managed to squeeze through a crack in the rock wall.”
“Open the door a crack.”
Crack (noun)
A sharply humorous comment; a wisecrack.
“I didn’t appreciate that crack about my hairstyle.”
Crack (noun)
A potent, relatively cheap, addictive variety of cocaine; often a rock, usually smoked through a crack-pipe.
Crack (noun)
The sharp sound made when solid material breaks.
“The crack of the falling branch could be heard for miles.”
Crack (noun)
Any sharp sound.
“The crack of the bat hitting the ball.”
Crack (noun)
An attempt at something.
“I’d like to take a crack at that game.”
Crack (noun)
Vagina.
“I’m so horny even the crack of dawn isn’t safe!”
Crack (noun)
The space between the buttocks.
“Pull up your pants! Your crack is showing.”
Crack (noun)
Conviviality; fun; good conversation, chat, gossip, or humorous storytelling; good company.
“The crack was good.”
“That was good crack.”
“He/she is quare good crack.”
“The party was great crack.”
Crack (noun)
Business; events; news.
“What’s the crack?”
“What’s this crack about a possible merger.”
Crack (noun)
A program or procedure designed to circumvent restrictions or usage limits on software.
“Has anyone got a crack for DocumentWriter 3.0?”
Crack (noun)
a meaningful chat.
Crack (noun)
Extremely silly, absurd or off-the-wall ideas or prose.
Crack (noun)
The tone of voice when changed at puberty.
Crack (noun)
A mental flaw; a touch of craziness; partial insanity.
“He has a crack.”
Crack (noun)
A crazy or crack-brained person.
Crack (noun)
A boast; boasting.
Crack (noun)
Breach of chastity.
Crack (noun)
A boy, generally a pert, lively boy.
Crack (noun)
A brief time; an instant; a jiffy.
“I’ll be with you in a crack.”
Crack (adjective)
Highly trained and competent.
“Even a crack team of investigators would have trouble solving this case.”
Crack (adjective)
Excellent, first-rate, superior, top-notch.
“She’s a crack shot with that rifle.”
Cocaine (noun)
an addictive drug derived from coca or prepared synthetically, used as an illegal stimulant and sometimes medicinally as a local anaesthetic.