An amphiphile (from the Greek αμφις, amphis: both and φιλíα, philia: love, friendship) is a chemical compound possessing both hydrophilic (water-loving, polar) and lipophilic (fat-loving) properties. Such a compound is called amphiphilic or amphipathic. This forms the basis for a number of areas of research in chemistry and biochemistry, notably that of lipid polymorphism. Organic compounds containing hydrophilic groups at both ends of a prolate (in the aggregate) molecule are called bolaamphiphilic. Common amphiphilic substances are soaps, detergents and lipoproteins.
misspelling of amphipathic
Describing a molecule, such as a detergent, which has both hydrophobic and hydrophilic groups.
Of the surface(s) on a protein, particularly an alpha helix, where one surface of the alpha helix has hydrophilic amino acids and the opposite face has hydrophobic (or lipophilic) amino acids.