Ketimine vs. Ketamine

Main Difference

The main difference between Ketimine and Ketamine is that the Ketimine is a any chemical compound having the structure RN=CR′R″, thus analogue of aldehyde or ketone in which an oxygen atom is replaced by substituted or unsubstituted nitrogen atom and Ketamine is a group of stereoisomers.

• Ketimine

  An imine ( or ) is a functional group or chemical compound containing a carbon–nitrogen double bond. The nitrogen atom can be attached to a hydrogen (H) or an organic group (R). If this group is not a hydrogen atom, then the compound can sometimes be referred to as a Schiff base. The carbon atom has two additional single bonds. The term “imine” was coined in 1883 by the German chemist Albert Ladenburg.

• Ketamine

  Ketamine, sold under the brand name Ketalar among others, is a medication mainly used for starting and maintaining anesthesia. It induces a trance-like state while providing pain relief, sedation, and memory loss. Other uses include for chronic pain and for sedation in intensive care. Heart function, breathing, and airway reflexes generally remain functional during its effects. Effects typically begin within five minutes when given by injection with the main effects lasting up to 25 minutes.Common side effects include psychological reactions as the medication wears off. These reactions may include agitation, confusion, or hallucinations. Elevated blood pressure and muscle tremors are relatively common, while low blood pressure and a decrease in breathing are less so. Spasms of the larynx may rarely occur. Ketamine is an NMDA receptor antagonist but it may also have other activity.Ketamine was discovered in 1962, first tested in humans in 1964, and was approved for use in the United States in 1970. Shortly after its US approval, it was extensively used for surgical anesthesia in the Vietnam War, due to its safety. It is on the World Health Organization’s List of Essential Medicines, the most effective and safe medicines needed in a health system. It is available as a generic medication. The wholesale cost in the developing world is between US$0.84 and US$3.22 per vial. Ketamine is also used as a recreational drug.

• Ketamine (noun)

  a synthetic compound used as an anaesthetic and analgesic drug and also (illicitly) as a hallucinogen.